Colorimetric Chemosensor for Sulfide Anion Detection Based on Symmetrical Nitrovanillin Azine

The nitrovanillin azine (NA) has been successfully synthesized and examined as a colorimetric chemosensor for sulfide anion detection. NA was using two steps reaction. Vanillin reacted with concentrated nitric acid to form 5-nitrovanillin (NV) then the NV condensed hydrazine hydrate produce NA. obtained fully elucidated by FTIR, 1H-NMR, 13C-NMR, GC-MS spectrometer. activity anionic carried out on several anions such F⁻, Cl⁻, Br⁻, I⁻, S2⁻, CN⁻, HCO3⁻, AcO⁻, H2PO4⁻, N3⁻, NO2⁻, SCN⁻, ClO3⁻, NO3⁻. tests showed only selective S2− in DMF:HEPES buffer (9:1, v/v, 10 mM, pH = 7.4) giving color change from light yellow dark green. LOD value 1.43 × 10−5 M interaction model of NA-S2− indicated deprotonation mode between -OH group ratio 1:1. can be applied qualitatively analysis filter paper strips quantitatively tap water.